Craig A Lygate Selected Research

Guanidinoacetate N-Methyltransferase (Guanidinoacetate Methyltransferase)

5/2005

Reduced inotropic reserve and increased susceptibility to cardiac ischemia/reperfusion injury in phosphocreatine-deficient guanidinoacetate-N-methyltransferase-knockout mice.

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Craig A Lygate Research Topics

Disease

16	Heart Failure 10/2020 - 06/2003
10	Myocardial Infarction 01/2017 - 06/2003
9	Hypertrophy 10/2014 - 06/2003
8	Reperfusion Injury 10/2018 - 05/2005
4	Infarction (Infarctions) 01/2021 - 04/2009
4	Hypoxia (Hypoxemia) 01/2019 - 05/2008
3	Cardiomegaly (Heart Hypertrophy) 05/2006 - 05/2005
3	Stroke (Strokes) 12/2005 - 02/2002
2	Obesity 10/2014 - 09/2013
2	Cardiomyopathies (Cardiomyopathy) 04/2014 - 06/2006
1	Diabetic Cardiomyopathies 01/2021
1	Disease Progression 10/2020
1	Aortic Valve Stenosis (Aortic Stenosis) 01/2020
1	Neoplasms (Cancer) 01/2019
1	Intellectual Disability (Idiocy) 01/2018
1	Atrophy 01/2018
1	Muscle Weakness 01/2018
1	Aneurysm (Aneurysms) 01/2018
1	Vascular Remodeling 01/2018
1	Abdominal Aortic Aneurysm 01/2018
1	Bradycardia 03/2015
1	Pain (Aches) 02/2015
1	Body Weight (Weight, Body) 10/2014
1	Left Ventricular Dysfunction 01/2014
1	Inflammation (Inflammations) 05/2013
1	Myocardial Stunning (Stunned Myocardium) 12/2012
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 12/2010
1	Insulin Resistance 07/2006
1	Ischemia 07/2006
1	Wolff-Parkinson-White Syndrome (Wolf-Parkinson-White Syndrome) 05/2006
1	Heart Diseases (Heart Disease) 11/2005

Drug/Important Bio-Agent (IBA)

13	CreatineIBA 01/2019 - 11/2005
6	creatine transporterIBA 01/2016 - 11/2005
5	Creatine Kinase (Creatine Phosphokinase)IBA 10/2018 - 06/2007
5	salicylhydroxamic acid (SHAM)IBA 01/2013 - 12/2005
4	Adenosine Triphosphate (ATP)IBA 04/2014 - 07/2006
3	Adenine NucleotidesIBA 01/2021 - 01/2013
3	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 07/2006
3	Phosphocreatine (Neoton)IBA 12/2012 - 05/2005
2	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 01/2019 - 07/2006
2	IsoenzymesIBA 01/2017 - 06/2007
2	Protein Isoforms (Isoforms)IBA 01/2017 - 06/2007
2	GlycogenIBA 10/2014 - 05/2006
2	AntioxidantsIBA 01/2014 - 12/2012
2	Adenosine Diphosphate (ADP)IBA 01/2013 - 11/2005
2	Nonesterified Fatty Acids (NEFA)IBA 04/2008 - 07/2006
2	Phosphates (Orthophosphate)IBA 04/2008 - 11/2005
2	Proteins (Proteins, Gene)FDA Link 07/2006 - 06/2006
2	Ventricular MyosinsIBA 06/2006 - 05/2005
2	Dobutamine FDA LinkGeneric 12/2005 - 05/2005
1	Mitochondrial Form Creatine KinaseIBA 10/2020
1	N 30IBA 01/2020
1	Angiotensin IIIBA 01/2018
1	sapropterin (tetrahydrobiopterin)FDA Link 01/2018
1	X-linked Creatine deficiencyIBA 01/2018
1	AnthracyclinesIBA 01/2017
1	Propidium (Propidium Iodide)IBA 01/2017
1	HomoarginineIBA 01/2017
1	Levodopa (L Dopa)FDA LinkGeneric 03/2015
1	Buprenorphine (Subutex)FDA LinkGeneric 02/2015
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2014
1	malonyl-CoA decarboxylaseIBA 10/2014
1	Protons (Proton)IBA 01/2014
1	LipidsIBA 09/2013
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 05/2013
1	Messenger RNA (mRNA)IBA 05/2013
1	CytokinesIBA 05/2013
1	Adenosine Monophosphate (AMP)IBA 01/2013
1	Ribose (D-Ribose)IBA 01/2013
1	Mitochondrial Permeability Transition PoreIBA 12/2012
1	FumaratesIBA 03/2012
1	Dimethyl FumarateIBA 03/2012
1	Isoflurane FDA LinkGeneric 09/2011
1	Adenylate KinaseIBA 12/2010
1	EnzymesIBA 12/2010
1	Phosphopyruvate Hydratase (Enolase)IBA 04/2010
1	triphenyltetrazoliumIBA 04/2009
1	GadoliniumIBA 04/2009
1	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 05/2008
1	Oxygen (Dioxygen)IBA 05/2008
1	Insulin (Novolin)FDA Link 07/2006
1	Phosphorus (Red Phosphorus)IBA 07/2006
1	UtrophinIBA 06/2006
1	TubulinIBA 06/2006
1	Cytoskeletal ProteinsIBA 06/2006
1	DesminIBA 06/2006
1	cysteine and glycine-rich protein 3IBA 06/2006
1	DystrophinIBA 06/2006
1	Arginine (L-Arginine)FDA Link 05/2006
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 05/2006
1	AMP-Activated Protein KinasesIBA 05/2006
1	A 7 (A-7)IBA 01/2006
1	Polypropylenes (Polypropylene)IBA 01/2006
1	Guanidinoacetate N-Methyltransferase (Guanidinoacetate Methyltransferase)IBA 05/2005

Therapy/Procedure

2	Therapeutics 01/2021 - 01/2019
2	Ligation 12/2010 - 06/2007
1	Induced Heart Arrest (Cardioplegia) 01/2016
1	Thoracotomy 02/2015
1	Analgesia 02/2015
1	Sutures (Suture) 01/2006